Scientists have developed a method of purification of cells infected with HIV. This discovery creates additional opportunities for the development of methods of combating this serious illness.
New technology of destruction of virus DNA help get rid of HIV Experts from Temple University used the technology of CRISPR/Cas9 for the purification of T lymphocytes from human immunodeficiency virus. It turned out that the system allows you to remove all copies of the viral genome and interfere with the re-introduction into the chromosome.
For observations used the CD4-receptors of T-lymphocytes, which are affected by HIV.
One gene of HIV, scientists replaced the gene of the fluorescent protein, so the opportunity to observe the behavior of the virus. The researchers noted that the RNA associated with the genes of the virus and have removed them from the genome.
The authors emphasized that this technology could be the basis for new treatments. The destruction of the DNA of the infected T lymphocytes will completely heal the body from the virus.
About the study informed the scientific publication “Scientific Reports”.